B7-33 (6mg)

1. Overview of B7-33 6mg

B7-33 is a first-in-class, single-chain soluble peptide mimetic of the human gene-2 relaxin (H2 relaxin) B-chain. It acts as a functionally selective agonist for the RXFP1 receptor, primarily activating the pERK1/2 signaling pathway to promote anti-fibrotic and vasodilatory effects without the detrimental cAMP-driven tumor promotion associated with full-length relaxin.

2. Key Benefits

• Main Effect: B7-33 is recognized for its potent anti-fibrotic activity, significantly reducing excessive collagen deposition and promoting the degradation of existing scar tissue in organs like the heart and lungs.
• Health Benefits: Research indicates substantial cardioprotective and vasoprotective advantages, including improved vascular compliance, enhanced blood vessel density, and the mitigation of cardiomyocyte hypertrophy.
• Optimization Efficiency: This peptide exhibits high efficiency in limiting infarct-related adverse remodeling and rapidly restoring tissue integrity and functional performance following injury in experimental models.

3. Usage & Storage Guidelines

Researchers must strictly follow established laboratory protocols during application. Note that storage is mandatory in the refrigerator at 2-8?C after reconstitution, and keep away from direct sunlight to avoid degradation of the peptide.

Note: This product is for laboratory research purposes only.